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Dr. Su Ryon Shin Featured in Nature for Breakthrough in biohybrid robots controlled by nerve cells and powered by cardiomyocytes

Dr. Su Ryon Shin’s pioneering work on biohybrid neuromuscular robots, recently published in Science Robotics, has been featured in Nature Reviews Bioengineering. This innovative study introduces a soft robot powered by living cardiac muscle cells and controlled by nerve cells integrated into a flexible hydrogel scaffold. The butterfly-shaped design includes a wireless artificial brain that directs motion through precise neural-to-muscle signal transmission, enabling adaptive and synchronous control. Dr. Shin’s research paves the way for advanced biohybrid systems with transformative potential in biomedical applications such as bionic prosthetics and pacemakers. Find the full article here

 
 
 

Su Ryon Shin, PhD Recognized as a Highly Cited Researcher for 2024

We are delighted to share that Dr. Su Ryon Shin has been recognized as a Highly Cited Researcher 2024 by the Web of Science. This distinction highlights her impactful contributions to science, with research that ranks in the top 1% by citations over the past decade. We are grateful for this recognition, which reflects Dr. Shin's dedication to advancing knowledge and innovation in her field.

 

Former Shin Lab Member Daniela Cavazos got accepted to pursue a PhD at MIT.

Daniela was a research trainee at the Shin Lab from January-March 2020, and she worked on developing a liver-on-a-chip platform with encapsulated co-culture spheroids to study hepatic fibrosis in vitro. She graduated Summa Cum Laude in December 2021 from Tecnológico de Monterrey, Campus Monterrey with a B.S. in Chemical Engineering and was the highest-ranking student of the graduating class. She just accepted an offer to pursue a Ph.D. in Chemical Engineering at MIT in the fall of 2022.

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Former Shin Lab Member Elmira Jalilian, PhD joins Department of Ophthalmology at the University of Illinois at Chicago (UIC) as Research Assistant Professor.

Dr. Elmira Jalilian is a Research Assistant Professor in the Department of Ophthalmology at the University of Illinois at Chicago (UIC). She is interested in studying novel stem cell and tissue engineering approaches as therapeutic method for corneal diseases. She was previously a postdoctoral fellow at the University of Michigan and Harvard Medical School. She completed her Ph.D. in Stem Cell Biology and Regenerative Medicine at University College London (UCL) and did her master’s in Medical Genetics at the University of Newcastle, UK. She did her bachelor’s in Cellular and Molecular Biology at Tehran University, Iran.  

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2020 Stepping Strong Breakthrough Award Su Ryon Shin, PhD

In collaboration with Olivier Pourquie and Indranil Sinha the Project ‘Using connective tissue biomaterials to improve muscle regeneration’ has been awarded by The Gillian Reny Center for Trauma Innovation. The purpose is to address the lose of large amounts of muscle tissue by the use of stem cell fate-controlling biomaterials.

Full review

 
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3D Printed Face Shields for Brigham & Women’s Hospital frontline workers

Dr. Su Ryon Shin, Dr. Shabir Hassan, & other members of the Shin Lab are making lightweight, reusable, 3D printed face shields for the frontline workers fighting Covid19 at the BWH. The initiative was in collaboration with Dr. Sherry Yu (Deland Fellow at BWH/Harvard Med) and kindly supported by the Stepping Strong foundation.

Slow motion video

 

Aikawa, Shin Win Department of Medicine 2020 Innovation Evergreen Fund Award

Elena Aikawa, MD, PhD, director of the Heart Valve Translational Research Program in the Division of Cardiovascular Medicine, and Su Ryon Shin, PhD, of the Division of Engineering in Medicine, received the Brigham Department of Medicine’s 2020 Innovation Evergreen Fund (IEF) award for their research project, “Engineering 3D Heart Valves Using Smart Biomaterials and Programmable 4D Bioprinting Technology.”

Full review

 

January birthdays at Shin Lab

Happy Birthday Mo, Niels , Yael and Kai

 

Congratulations to our research trainees!

Congratulations Eder Luna and Luis García our research trainees from Tecnológico de Monterrey , México for getting their covers published for Advanced Functional Materials Journal and ACS Publications Journals.

We encourage new team members to participate not just with the experiments, but in the development of the figures and covers for the papers.

 
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Brazilian Party

We like showing and sharing the culture with of each our members.

 

KIST-HMS International Symposium: Biomaterials for Translational Research

On October 22, scientists from around the world met in in the KIST-HMS International symposium to present their research for the development of novel biomaterials. Presentation topics ranged from nanotherapy to exciting applications in bioprinting and even materials that pose alternatives to surgical intervention.

Find the full program here.

 
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BWH Clinical & Research News

Together, Collaborators Take Steps Toward Muscle Regeneration

Stepping Strong Innovator Award recipients Su-Ryon Shin, PhD, and Indranil Sinha, MD, are working together to restore skeletal muscle mass and function using 3-D bioprinting


(Left to right): Giorgio Giatsidis, MD, Indranil Sinha, MD, Su-Ryon Shin, PhD, Eric Goralnick, MD, MS, Morteza Mahmoudi, PhD, Omid Farokhzad, MD, Bohdan Pomahac MD, Branislav Kollar, MD, and Sotirios Tasigiorgos, MD

(Left to right): Giorgio Giatsidis, MD, Indranil Sinha, MD, Su-Ryon Shin, PhD, Eric Goralnick, MD, MS, Morteza Mahmoudi, PhD, Omid Farokhzad, MD, Bohdan Pomahac MD, Branislav Kollar, MD, and Sotirios Tasigiorgos, MD

Congratulations, 2018 Stepping Strong Innovator Award Winners!

On January 22, members of the Stepping Strong Medical Executive Committee and the Stepping Strong Advisory Board heard pitches from five research teams—four seeking additional Innovator Awards funding for existing projects, and one requesting funding for a new project. Stepping Strong is thrilled to grant awards to all five teams. Read more about the winning projects below, and enjoy photos from the event.

Su-Ryon Shin, PhD, and Indranil Sinha, MD,
Restoring skeletal muscle mass and function using 3D bioprinting

$100,000 to develop vascular channels to improve scaffold binding to tissue, optimize growth factors to promote skeletal muscle regeneration and to develop a research agenda around 3D bio-printing and scaffolding.


2015 Winner: Su Ryon Shin, PhD.

2015 Winner: Su Ryon Shin, PhD.

Congratulations, 2015 Stepping Strong Innovator Award Winner! Su-Ryon Shin, PhD

Project
3-D bioprinting: A new approach to healing muscle trauma

Tissue engineering has emerged as a promising way to create 3-D tissue for patients who have lost muscle through traumatic injuries. However, developing muscle tissue that functions as real muscle remains a challenge. Shin and her team have addressed this obstacle by introducing an entirely new approach: bioprinting. Through bioprinting, the team creates 3-D muscle tissue that contains blood vessels and mimics living cells. This advanced technology has the potential to create significant economic savings by treating muscle trauma without requiring muscle organ donors.