Shin Laboratory Members
Assistant Professor, Principal Investigator
Su Ryon Shin, Ph.D.
Su Ryon Shin is an Assistant Professor and Principal Investigator of Medicine at Brigham and Women's Hospital, Harvard Medical School. Dr. Shin received a doctoral degree from Hanyang University, South Korea. In Nov. 2010, she joined Prof. Ali Khademhosseini's group at Brigham and Women's Hospital, Harvard Medical School, Harvard-MIT Division of Health Sciences and Technologies, and Wyss Institute for Biologically Inspired Engineering as a Postdoctoral Research Fellow. Dr. Shin is an expert in the field of nanomaterials, biomaterials, tissue engineering, electrochemical actuator, biosensor, organ-on-a-chip, and 3D bioprinting.
Postdoctoral Research Fellows
Myung Chul Lee
Dr. Myung Chul Lee is a postdoctoral fellow in Shin’s lab since Feb 2021. During his master's course, he performed regenerative medical research using adult stem cells and scaffolds, and developed a device for gene transfection. In his Ph.D. course, he studied targeting cancer therapy for glioblastoma multiforme (brain tumor) using CRISPR based non-viral delivery systems. He is well accomplished and trained in designing new gene/drug delivery carriers, selection of target molecules, in vitro, and in vivo tumor models, and clinical application-specific studies. He has focused on genetic engineering and biological engineering, ultimately aiming for bio-convergence of his research findings into biosystems engineering.
Nicole Joy Bassous
Nicole Joy Bassous is a Postdoctoral Fellow in Dr. Su Ryon Shin’s Tissue Engineering and Biomaterials Laboratory at Brigham and Women’s Hospital, Harvard Medical School, HST. Her postdoctoral work postulates the design of artificial tissues that are functionalized to repair or replace damaged organs or organ structures. Dr. Bassous’ current research goals are to lead in the elaboration of mechanisms for manufacturing viable tissues and organs (tissue engineering applications) or medicinal nanoparticles and drug carrier devices (drug delivery applications); to study the influence of biological, mechanical, and chemical parameters or input materials on disease progression, inflammation, (re)cellularization and tissue function, as enforced by the appropriate assays; and to establish biofunctional products, especially by incorporating concepts in tissue engineering (especially, cardiac), 3-D bioprinting, materials science, drug delivery, cell biology, genetic engineering molecular sensing, immunology, and microbiology.
Niyou Wang
Dr. Niyou Wang is a postdoctoral researcher in Professor Su Ryon Shin’s lab at Brigham and Women’s Hospital, Harvard Medical School. He received his B.S (2011), M.S. (2015) and Ph.D. (2021) degrees in Mechanical Engineering from National University of Singapore. He has rich experience in 3D printing, bioprinting, bone tissue engineering, nanoparticles, and mechanical engineering. During his Ph.D. study, he mainly developed novel metallic structures for bone implants and explored their potential long-term side effects. He expanded his postdoctoral research to bioprinting and tissue engineering, including 3D printed conductive polymeric scaffolds and 3D bioprinting of cell-laden hydrogel for guided tissue regeneration. In Aug 2022, he joined the Shin lab as a postdoc fellow, where he will focus on bioprinting, tissue engineering, and novel oxygen-releasing materials.
Zahra Rezaei
Zahra has a Ph.D. in Chemical Engineering from Sharif University of Technology, Iran. She is working on electrochemical-based micro-biosensors for early detection of diseases. Her interests include developing biosensors, microfluidic devices and organs on a chip. Zahra joined Dr. Shin’s lab since May 2019. She is collaborating with Mara Nanotech Korea, Inc. for developing cardiac biosensors at this moment.
Da-Seul Kim
Dr. Da-Seul Kim is a Postdoctoral Fellow in Dr. Su Ryon Shin’s lab at Brigham and Women’s Hospital, Harvard Medical School since Sep 2023. Dr. Kim earned her M.S. (2018) and Ph.D. (2023) degrees in the Department of Integrative Engineering (Biomedical) from Chung-Ang University, Korea. Concurrently, she serves as a research professor at CHA University, Korea. Dr. Kim brings a wealth of experience to her work, specializing in tissue engineering and regenerative medicine, with a focus on utilizing functionalized biocompatible polymers for diverse tissue applications. She is currently dedicated to the goal of various tissue regeneration through the utilization of nano- and micro-materials via 3D printing.
Jeongwook Seo
Dr. Jeongwook Seo is a postdoctoral researcher in Professor Suryon Shin’s lab at Brigham and Women’s Hospital, Harvard Medical School. He is a leading researcher in the field of biomaterials and bioprinting, specializing in the development of hydrogels for applications in tissue engineering. His innovative research has resulted in the development of a hybrid-crosslinking hydrogel and a DLP bioprinting system, leading to new applications such as 4D printing scaffolds, printed cell-cultured meat, and printed thermo-sensitive microneedles. Currently, his research focuses on tissue engineering using robotic arm and DLP bioprinting, aiming to pioneer various applications in this field.
Kannan Govindaraj
Dr. Kannan Govindaraj is a Marie-Curie post-doctoral fellow at Professor Su Ryon Shin’s lab at Brigham and Women’s Hospital, Harvard Medical School. He has expertise in advanced quantitative fluorescence microscopy and molecular cell biology methods. For his doctoral research, under the supervision of Dr. Janine Post, he investigated transcription factor dynamics in osteoarthritis pathology using quantitative fluorescence microscopy methods (TF-FRAP) and obtained his PhD from the University of Twente, The Netherlands. During his first post-doctoral appointment at Prof. dr. Jeroen Leijten’s lab at the University of Twente, he investigated the role of intracellular Molecular crowding in osteoarthritis pathology. Previously, he worked at the Center for Cellular and Molecular Biology (CCMB), India as a Junior Research Fellow. He obtained his bachelor’s and master’s degree in molecular Biosciences from Bishop Heber College, India. Currently, he is working on novel biomaterials to control and guide cell function in engineered tissues. He has presented his work in more than 20 international conferences and received several travel grant awards.
Yeongseok Jang
Dr. Yeongseok Jang is a postdoctoral researcher in Professor Shin’s lab at Brigham and Women’s Hospital, Harvard Medical School. He received his B.S (2014), M.S. (2016) and Ph.D. (2020) degrees in Mechanical Design Engineering from Jeonbuk National University. He is leading research on microfluidics, biosensor, organ-on-a-chip, tissue engineering, porous structure, optomechanics. He will focus on cell-laden bioprinting for volumetric muscle loss.
Ph.D. Students
Cholong Choi
Cholong Choi focuses on developing new functional biomaterials from nano to macro scale for various biomedical applications. Her research interest is to provide novel biomaterials to attain the same level of complexity and reliability seen in biological systems to understand the cell response. To do so, she has a strong background in to analyze and develop a 3D hydrogel systems for disease treatment and tissue engineering by (1) synthesizing functional biomaterials to control physicochemical properties and (2) fabricating nano-composite hydrogel in multiscale. She is presently engaged in the development of an in vivo compatible platforms using functional hydrogel.
Masters Students
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Undergraduate Students
Javier Alejandro Lozano Soto
Álvaro Dario Martínez Blanco
Montserrat Legorreta González
Monserrat is a 5th-year Biotechnology Engineering student at Tecnológico de Monterrey. Her academic journey has been marked by active involvement in diverse research initiatives. Notably, she has contributed to pioneering projects focused on creating novel treatments for type 2 diabetes using nutraceuticals collaborating closely with BioMaker Nutrition. Additionally, her research delved into the phenotype of multidrug-resistant enterotoxigenic Escherichia coli found in street food in pediatric patients at Toluca's Children’s Hospital has resulted in a study that garnered five awards across local and national scientific exhibitions. Her repertoire extends to crafting clinical protocols for Phase 1 pharmaceutical studies in partnership with Sanofi, facilitating shoot growth in potato plants via tissue culture to enhance yield and quality in her city with Bosky MX, and designing bacterial biofactories aimed at treating industrial wastewater by producing enzymes. Monserrat's academic excellence and scholarships have paved the way for her participation in international United Nations models, where she passionately represented her country across diverse global topics.
Within our laboratory, Monserrat plays a pivotal role in cutting-edge regenerative medicine projects centered on tissue engineering. She actively contributes to evaluating the therapeutic potential of exosomes across various pathologies, while also aiding in the development of delivery systems to induce apoptosis in lung cancer cells.
Santiago Ramirez Castillo
Santiago Ramirez Castillo is an undergraduate student of Biomedical Engineering at the Monterrey campus of Tecnologico de Monterrey. He is passionate about medical innovation and has experience in tissue engineering and bioinstrumentation. He worked as a research trainee in his university's materials lab, focusing on developing a TAVR replacement simulator. He joined Shin Lab in January 2024 and is currently working on manufacturing biomimetic scaffolds to promote skeletal muscle regeneration.
Giovanna Romero
Giovanna Romero is a senior Mechatronics Engineering undergraduate student at Tecnológico de Monterrey. Her research interests include microfluidics, additive manufacturing and electrochemical sensing technologies. In 2023, she was selected as a Mitacs Globalink Research Intern to join the Microfluidics and Nanotechnology Laboratory at the University of Victoria, where she worked in the development of an embedded system relying on Metal Oxide Sensors for artificial olfaction and Machine Learning models for Hazardous Household Waste classification. Her current work relates to CAD design and fluid delivery automation for microfluidic chips. She is also a volunteer at the MIT CSAIL App Inventor research group working on Internet of Things and AI-based mobile applications.
Carolina Vazquez
Carolina Vazquez, a senior biotechnology student at Tecnológico de Monterrey, joined Sr. Su Ryon Shin's laboratory at Brigham and Women's Hospital, Harvard Medical School in February 2024. Her interests span tissue engineering, molecular biology, biochemical engineering, cell biology, and process optimization. With a background in finance and quality control, she previously interned at Schneider Electric, winning the Summer Innovation Challenge 2023. She has experience in optimizing production processes with FEMSA, including the maximization of M cherry production. Additionally, she has expertise in wastewater treatment and collaborated on developing methods for alkaloid removal in partnership with Tecnológico de Monterrey and the Pontificia Universidad Católica del Ecuador
José Joaquín Velasco Carphio
José Joaquín Velasco Carphio is a senior undergraduate student majoring in Chemical Engineering with a minor in Biotechnology at Tecnológico de Monterrey. He has a keen interest in bioprocess engineering and control within the pharmaceutical sector. José has led projects related to additive manufacturing and process intensification, including the development of a 3D printed carbon dioxide filter for Direct Air Capture. He is a former winner of the national event ExpoIngenierías, December 2023 edition. He is currently involved in projects related to microRNA delivery, regenerative medicine, and 3D bioprinting, with a goal of contributing to advancements in biomedical and pharmaceutical technologies. His research interests include additive manufacturing, process intensification, and the development of drug delivery platforms.